Journal article

Early-life exposures predicting onset and resol of childhood overweight or obesity

JA Kerr, C Long, SA Clifford, J Muller, AN Gillespie, S Donath, M Wake

Archives of Disease in Childhood | BMJ PUBLISHING GROUP | Published : 2017

Abstract

Objectives: To determine which of multiple early-life exposures predict onset or resolution of overweight/obesity during a 9-year period. Methods: Design: longitudinal cohort from three harmonised community-based cohorts enriched for overweight and obesity. Early-life exposures: child-gestational age; delivery; birth weight; breast feeding; solids introduction; baseline body mass index (BMI); waist circumference; diet; activity; global, physical and psychosocial health. Mother-baseline BMI; education; age; neighbourhood disadvantage; concern for child's weight. Outcome: change in BMI category. Analyses: adjusted logistic regression. Results: On average, the 363 children (57% retention) were ..

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Grants

Awarded by Murdoch Children's Research Institute


Funding Acknowledgements

The harmonised 2014 wave of the LEAP, PEAS and HopSCOTCH studies was funded by the Murdoch Childrens Research Institute. The HopSCOTCH trial was funded by Australian National Health and Medical Research Council (NHMRC) General Practice Clinical Research Program Grant (491212); the LEAP 2 trial by NHMRC Project Grant 334309; and the PEAS by NHMRC Project Grant 284509. MW was supported by NHMRC Senior Research Fellowship 1046518, and Alanna Hanvey by Australian Postgraduate Award. The funding organisations did not have a role in the design and conduct of the study; collection, management, analysis and interpretation of the data; or in the preparation, review or approval of the manuscript. Research at the Murdoch Children's Research Institute is supported by the Victorian Government's Operational Infrastructure Support Program.